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The safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of CH4987655 in healthy volunteers: target suppression using a biomarker.
Lee, Lucy; Niu, Huifeng; Rueger, Ruediger; Igawa, Yuriko; Deutsch, Jonathan; Ishii, Nobuya; Mu, Song; Sakamoto, Yuuichiro; Busse-Reid, Rachel; Gimmi, Claude; Goelzer, Petra; De Schepper, Stefanie; Yoshimura, Yashushi; Barrett, Joanne; Ishikawa, Yuji; Weissgerber, Georges; Peck, Richard.
Affiliation
  • Lee L; Clinical Pharmacology, Hoffman-La Roche, Nutley, New Jersey 07110, USA. lucy.lee@roche.com
Clin Cancer Res ; 15(23): 7368-74, 2009 Dec 01.
Article in En | MEDLINE | ID: mdl-19934286
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Administration, Oral / Enzyme Inhibitors Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States
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Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Administration, Oral / Enzyme Inhibitors Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States