Neolignans from plants in northeastern Brazil (Lauraceae) with activity against Trypanosoma cruzi.

Cabral, M M O; Barbosa-Filho, J M; Maia, G L A; Chaves, M C O; Braga, M V; De Souza, W; Soares, R O A

Cabral, M M O; Barbosa-Filho, J M; Maia, G L A; Chaves, M C O; Braga, M V; De Souza, W; Soares, R O A.

Affiliation

Cabral MM; Laboratório de Diptera, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, 21045-900 Rio de Janeiro, RJ, Brazil. mmaleck@ioc.fiocruz.br

Exp Parasitol ; 124(3): 319-24, 2010 Mar.

Article in En | MEDLINE | ID: mdl-19944690

Subject(s)

Benzofurans/pharmacology; Lignans/pharmacology; Macrophages, Peritoneal/drug effects; Trypanocidal Agents/pharmacology; Trypanosoma cruzi/drug effects; Animals; Benzofurans/chemistry; Benzofurans/toxicity; Blood Transfusion/standards; Brazil; Cell Survival/drug effects; Chagas Disease/prevention & control; Chagas Disease/transmission; Humans; Inhibitory Concentration 50; Lignans/chemistry; Lignans/toxicity; Macrophages, Peritoneal/cytology; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Plant Extracts/chemistry; Plant Extracts/pharmacology; Plant Extracts/toxicity; Trypanocidal Agents/chemistry; Trypanocidal Agents/toxicity; Trypanosoma cruzi/growth & development; Trypanosoma cruzi/ultrastructure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanocidal Agents / Trypanosoma cruzi / Benzofurans / Macrophages, Peritoneal / Lignans Limits: Animals / Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Exp Parasitol Year: 2010 Document type: Article Affiliation country: Brazil Country of publication: United States

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