Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.

Azzato, Elizabeth M; Chen, Renee A; Wacholder, Sholom; Chanock, Stephen J; Klebanoff, Mark A; Caporaso, Neil E

Azzato, Elizabeth M; Chen, Renee A; Wacholder, Sholom; Chanock, Stephen J; Klebanoff, Mark A; Caporaso, Neil E.

Affiliation

Azzato EM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland 20852, USA. azzatoe2@mail.nih.gov

Pharmacogenet Genomics ; 20(1): 58-63, 2010 Jan.

Article in En | MEDLINE | ID: mdl-19952982

Subject(s)

Abnormalities, Drug-Induced/genetics; Anticonvulsants/adverse effects; Craniofacial Abnormalities/chemically induced; Epoxide Hydrolases/genetics; Phenytoin/adverse effects; Polymorphism, Genetic/genetics; Adolescent; Adult; Anticonvulsants/pharmacokinetics; Confidence Intervals; Craniofacial Abnormalities/genetics; Female; Genotype; Haplotypes; Humans; Logistic Models; Odds Ratio; Phenytoin/pharmacokinetics; Polymorphism, Single Nucleotide/genetics; Pregnancy; Risk Factors; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenytoin / Polymorphism, Genetic / Abnormalities, Drug-Induced / Craniofacial Abnormalities / Epoxide Hydrolases / Anticonvulsants Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Pregnancy Language: En Journal: Pharmacogenet Genomics Journal subject: FARMACOLOGIA / GENETICA MEDICA Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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