Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication.

Baker, B J; Dotzlaf, J E; Yeh, W K

Baker, B J; Dotzlaf, J E; Yeh, W K.

Affiliation

Baker BJ; Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285.

J Biol Chem ; 266(8): 5087-93, 1991 Mar 15.

Article in En | MEDLINE | ID: mdl-2002049

Subject(s)

Oxygenases; Streptomyces/enzymology; Amino Acid Sequence; Biological Evolution; Cephalosporins/biosynthesis; Cephamycins/biosynthesis; Chromatography, Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Molecular Weight; Oxygenases/antagonists & inhibitors; Oxygenases/genetics; Oxygenases/isolation & purification; Oxygenases/metabolism; Penicillins/pharmacology; Sequence Homology, Nucleic Acid

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Collection: 01-internacional Database: MEDLINE Main subject: Oxygenases / Streptomyces Language: En Journal: J Biol Chem Year: 1991 Document type: Article

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Oxygenases / Streptomyces Language: En Journal: J Biol Chem Year: 1991 Document type: Article