Cyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.

Salem, Mohamed L; El-Naggar, Sabry A; Cole, David J

Salem, Mohamed L; El-Naggar, Sabry A; Cole, David J.

Affiliation

Salem ML; Surgery Department and Hollings Cancer Center, Medical University of South Carolina, Charleston, 29425, USA. salemm@musc.edu

Cell Immunol ; 261(2): 134-43, 2010.

Article in En | MEDLINE | ID: mdl-20036354

Subject(s)

Antigen Presentation/drug effects; Antineoplastic Agents, Alkylating/pharmacology; Bone Marrow Cells/drug effects; Cyclophosphamide/pharmacology; Dendritic Cells/drug effects; Dendritic Cells/immunology; T-Lymphocytes; Adoptive Transfer; Animals; Antigen Presentation/immunology; Bone Marrow Cells/cytology; Bone Marrow Cells/immunology; CD11 Antigens/immunology; Dendritic Cells/cytology; Female; Immunologic Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Antigen, T-Cell/genetics; Receptors, Antigen, T-Cell/immunology; Stem Cells/cytology; Stem Cells/drug effects; Stem Cells/immunology; T-Lymphocytes/drug effects; T-Lymphocytes/immunology; Toll-Like Receptors/agonists; Toll-Like Receptors/immunology; Transplantation Conditioning

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Bone Marrow Cells / T-Lymphocytes / Antigen Presentation / Antineoplastic Agents, Alkylating / Cyclophosphamide Limits: Animals Language: En Journal: Cell Immunol Year: 2010 Document type: Article Affiliation country: United States Country of publication: Netherlands

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