Sleep disordered breathing is associated with appropriate implantable cardioverter defibrillator therapy in congestive heart failure patients.
Clin Cardiol
; 33(2): E27-30, 2010 Feb.
Article
in En
| MEDLINE
| ID: mdl-20043344
BACKGROUND: Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population. HYPOTHESIS: To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients. METHODS: A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography. RESULTS: A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = - 0.619; P = .003, respectively). CONCLUSIONS: Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Arrhythmias, Cardiac
/
Primary Prevention
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Sleep Apnea Syndromes
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Electric Countershock
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Defibrillators, Implantable
/
Heart Failure
Type of study:
Diagnostic_studies
/
Etiology_studies
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Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Aged
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
Clin Cardiol
Year:
2010
Document type:
Article
Affiliation country:
Italy
Country of publication:
United States