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Sleep disordered breathing is associated with appropriate implantable cardioverter defibrillator therapy in congestive heart failure patients.
Tomaello, Luca; Zanolla, Luisa; Vassanelli, Corrado; LoCascio, Vincenzo; Ferrari, Marcello.
Affiliation
  • Tomaello L; Department of Biomedical and Surgical Sciences, University of Verona, Italy. luca.tomaello@libero.it
Clin Cardiol ; 33(2): E27-30, 2010 Feb.
Article in En | MEDLINE | ID: mdl-20043344
BACKGROUND: Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population. HYPOTHESIS: To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients. METHODS: A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography. RESULTS: A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = - 0.619; P = .003, respectively). CONCLUSIONS: Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arrhythmias, Cardiac / Primary Prevention / Sleep Apnea Syndromes / Electric Countershock / Defibrillators, Implantable / Heart Failure Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Aged / Humans / Male / Middle aged Language: En Journal: Clin Cardiol Year: 2010 Document type: Article Affiliation country: Italy Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arrhythmias, Cardiac / Primary Prevention / Sleep Apnea Syndromes / Electric Countershock / Defibrillators, Implantable / Heart Failure Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Aged / Humans / Male / Middle aged Language: En Journal: Clin Cardiol Year: 2010 Document type: Article Affiliation country: Italy Country of publication: United States