Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures.

Lee, Eun Ok; Park, Hee Ju; Kang, Jihee Lee; Kim, Hye-Sun; Chong, Young Hae

Lee, Eun Ok; Park, Hee Ju; Kang, Jihee Lee; Kim, Hye-Sun; Chong, Young Hae.

Affiliation

Lee EO; Department of Microbiology, School of Medicine, Ewha Medical Research Institute, Ewha Womans University, Seoul, Korea.

J Neurochem ; 112(6): 1477-87, 2010 Mar.

Article in En | MEDLINE | ID: mdl-20050970

Subject(s)

Chemokine CCL2/metabolism; Enzyme Inhibitors/pharmacology; Gene Expression Regulation/drug effects; Hippocampus/drug effects; Hippocampus/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Signal Transduction/drug effects; Stilbenes/pharmacology; Animals; Animals, Newborn; Antibodies/pharmacology; Chemokine CCL2/genetics; Chemokine CCL2/immunology; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay/methods; Glutamic Acid/pharmacology; Interleukin-1beta/immunology; Interleukin-1beta/metabolism; L-Lactate Dehydrogenase/metabolism; Organ Culture Techniques; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Resveratrol

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Signal Transduction / Gene Expression Regulation / Chemokine CCL2 / Mitogen-Activated Protein Kinase 3 / Enzyme Inhibitors / Hippocampus Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neurochem Year: 2010 Document type: Article Country of publication: United kingdom

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