Aminodextran containing magnetite nanoparticles for molecular biology applications: preparation and evaluation.
J Biomed Nanotechnol
; 5(2): 172-81, 2009 Apr.
Article
in En
| MEDLINE
| ID: mdl-20055095
ABSTRACT
Within the framework of medical diagnosis, the main objective is the development of hydrophilic magnetic particles for the generic capture of the nucleic acids in order to enhance the sensitivity. The strategy used in this work is based on the synthesis of cationic and hydrophilic magnetic nanoparticles bearing aminodextran. The synthesis was performed using two different processes (i) coprecipitation of the ferrous and ferric salts in the presence of an aqueous solution of aminodextran and (ii) via adsorption of aminodextran on iron oxide nanoparticles. The obtained particles are characterized and evaluated in non-specific nucleic acids extraction and amplification.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drug Carriers
/
Dextrans
/
Crystallization
/
Nanostructures
/
Ferrosoferric Oxide
/
Molecular Biology
Type of study:
Evaluation_studies
Language:
En
Journal:
J Biomed Nanotechnol
Year:
2009
Document type:
Article
Affiliation country:
France