Generation of designer receptors exclusively activated by designer drugs (DREADDs) using directed molecular evolution.

Pei, Ying; Dong, Shuyun; Roth, Bryan L

Pei, Ying; Dong, Shuyun; Roth, Bryan L.

Affiliation

Pei Y; University of North Carolina, Chapel Hill, North Carolina, USA.

Curr Protoc Neurosci ; Chapter 4: Unit 4.33, 2010 Jan.

Article in En | MEDLINE | ID: mdl-20066658

Subject(s)

Directed Molecular Evolution/methods; Drug Design; Receptors, G-Protein-Coupled/genetics; Receptors, G-Protein-Coupled/metabolism; Designer Drugs/metabolism; Gene Library; Humans; Mutation; Yeasts

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Directed Molecular Evolution / Receptors, G-Protein-Coupled Limits: Humans Language: En Journal: Curr Protoc Neurosci Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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