Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-claudin-1 associations.

Krieger, Sophie E; Zeisel, Mirjam B; Davis, Christopher; Thumann, Christine; Harris, Helen J; Schnober, Eva K; Mee, Christopher; Soulier, Eric; Royer, Cathy; Lambotin, Mélanie; Grunert, Fritz; Dao Thi, Viet Loan; Dreux, Marlène; Cosset, François-Loïc; McKeating, Jane A; Schuster, Catherine; Baumert, Thomas F

Krieger, Sophie E; Zeisel, Mirjam B; Davis, Christopher; Thumann, Christine; Harris, Helen J; Schnober, Eva K; Mee, Christopher; Soulier, Eric; Royer, Cathy; Lambotin, Mélanie; Grunert, Fritz; Dao Thi, Viet Loan; Dreux, Marlène; Cosset, François-Loïc; McKeating, Jane A; Schuster, Catherine; Baumert, Thomas F.

Affiliation

Krieger SE; Institut National de la Santé et de la Recherche Médicale, U748, Strasbourg, France.

Hepatology ; 51(4): 1144-57, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20069648

Subject(s)

Antibodies/pharmacology; Antigens, CD/immunology; Cell Adhesion Molecules/immunology; Hepatitis C/therapy; Membrane Proteins/physiology; 12E7 Antigen; Antigens, CD/physiology; Claudin-1; Humans; Immunization; Membrane Proteins/immunology; Neutralization Tests; Scavenger Receptors, Class B/physiology; Tetraspanin 28; Tight Junctions/physiology; Virus Internalization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antigens, CD / Cell Adhesion Molecules / Hepatitis C / Membrane Proteins / Antibodies Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Hepatology Year: 2010 Document type: Article Affiliation country: France

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