Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine.

Foster, A E; Okur, F V; Biagi, E; Lu, A; Dotti, G; Yvon, E; Savoldo, B; Carrum, G; Goodell, M A; Heslop, H E; Brenner, M K

Foster, A E; Okur, F V; Biagi, E; Lu, A; Dotti, G; Yvon, E; Savoldo, B; Carrum, G; Goodell, M A; Heslop, H E; Brenner, M K.

Affiliation

Foster AE; Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, Houston, TX 77030, USA. aefoster@txccc.org

Leukemia ; 24(3): 563-72, 2010 Mar.

Article in En | MEDLINE | ID: mdl-20072155

Subject(s)

CD40 Ligand/immunology; Cancer Vaccines/immunology; Leukemia, Lymphocytic, Chronic, B-Cell/therapy; T-Lymphocytes, Cytotoxic/immunology; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters/physiology; Adult; Aged; Antigens, CD19/analysis; CD5 Antigens/analysis; Drug Resistance, Neoplasm; Extracellular Matrix Proteins/genetics; Female; Humans; Hyaluronan Receptors/genetics; Immunization; Leukemia, Lymphocytic, Chronic, B-Cell/immunology; Male; Middle Aged; Neoplasm Proteins/physiology; Vidarabine/analogs & derivatives; Vidarabine/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Leukemia, Lymphocytic, Chronic, B-Cell / Cancer Vaccines / CD40 Ligand Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2010 Document type: Article Affiliation country: United States

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