The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: the role of tumor necrosis factor-alpha.

Zhong, Yi; Zhou, Li-Jun; Ren, Wen-Jie; Xin, Wen-Jun; Li, Yong-Yong; Zhang, Tong; Liu, Xian-Guo

Zhong, Yi; Zhou, Li-Jun; Ren, Wen-Jie; Xin, Wen-Jun; Li, Yong-Yong; Zhang, Tong; Liu, Xian-Guo.

Affiliation

Zhong Y; Pain Research Center, Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

Brain Behav Immun ; 24(6): 874-80, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20116424

Subject(s)

Microglia/enzymology; Microglia/physiology; Nerve Fibers, Unmyelinated/physiology; Neuronal Plasticity/physiology; Posterior Horn Cells/physiology; Synapses/physiology; Tumor Necrosis Factor-alpha/physiology; src-Family Kinases/physiology; Animals; Anti-Bacterial Agents/pharmacology; Blotting, Western; Electrophysiology; Immunohistochemistry; Long-Term Potentiation/drug effects; Long-Term Potentiation/physiology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Minocycline/pharmacology; Protein Kinase Inhibitors/pharmacology; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor, Type I/genetics; src-Family Kinases/antagonists & inhibitors; src-Family Kinases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Tumor Necrosis Factor-alpha / Microglia / Src-Family Kinases / Posterior Horn Cells / Nerve Fibers, Unmyelinated / Neuronal Plasticity Limits: Animals Language: En Journal: Brain Behav Immun Journal subject: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Year: 2010 Document type: Article Affiliation country: China Country of publication: Netherlands

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