Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling.

Singh, Shree Ram; Zheng, Zhiyu; Wang, Hong; Oh, Su-Wan; Chen, Xiu; Hou, Steven X

Singh, Shree Ram; Zheng, Zhiyu; Wang, Hong; Oh, Su-Wan; Chen, Xiu; Hou, Steven X.

Affiliation

Singh SR; Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA. singhshr@mail.nih.gov

J Cell Physiol ; 223(2): 500-10, 2010 May.

Article in En | MEDLINE | ID: mdl-20143337

Subject(s)

Drosophila Proteins/metabolism; Drosophila melanogaster/metabolism; Germ Cells/metabolism; Janus Kinases/metabolism; STAT Transcription Factors/metabolism; Stem Cell Niche/physiology; Stem Cells/metabolism; Testis/metabolism; Transcription Factors/metabolism; Animals; Cell Communication/physiology; Cell Differentiation/physiology; Drosophila Proteins/genetics; Drosophila melanogaster/embryology; Drosophila melanogaster/genetics; Gene Expression Regulation, Developmental/physiology; Germ Cells/cytology; Germ-Line Mutation/genetics; Janus Kinases/genetics; Male; STAT Transcription Factors/genetics; Signal Transduction/physiology; Spermatogenesis/physiology; Stem Cells/cytology; Suppressor of Cytokine Signaling Proteins/genetics; Suppressor of Cytokine Signaling Proteins/metabolism; Testis/cytology; Testis/embryology; Transcription Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Testis / Transcription Factors / Drosophila Proteins / Drosophila melanogaster / STAT Transcription Factors / Janus Kinases / Stem Cell Niche / Germ Cells Limits: Animals Language: En Journal: J Cell Physiol Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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