Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.

Blundell, Jacqueline; Blaiss, Cory A; Etherton, Mark R; Espinosa, Felipe; Tabuchi, Katsuhiko; Walz, Christopher; Bolliger, Marc F; Südhof, Thomas C; Powell, Craig M

Blundell, Jacqueline; Blaiss, Cory A; Etherton, Mark R; Espinosa, Felipe; Tabuchi, Katsuhiko; Walz, Christopher; Bolliger, Marc F; Südhof, Thomas C; Powell, Craig M.

Affiliation

Blundell J; Departments of Neurology and Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas, 75390-8813, USA.

J Neurosci ; 30(6): 2115-29, 2010 Feb 10.

Article in En | MEDLINE | ID: mdl-20147539

Subject(s)

Grooming; Membrane Proteins/genetics; Memory; Nerve Tissue Proteins/genetics; Spatial Behavior; Stereotyped Behavior; Animals; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Cerebral Cortex/physiology; Corpus Striatum/physiology; Cycloserine/pharmacology; Drug Partial Agonism; Excitatory Postsynaptic Potentials; Hippocampus/physiology; Long-Term Potentiation; Maze Learning; Membrane Proteins/physiology; Mice; Mice, Knockout; Nerve Tissue Proteins/physiology; Neural Cell Adhesion Molecules/metabolism; Patch-Clamp Techniques; Receptors, AMPA/metabolism; Receptors, N-Methyl-D-Aspartate/agonists; Receptors, N-Methyl-D-Aspartate/metabolism; Social Behavior; Synapses/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spatial Behavior / Stereotyped Behavior / Grooming / Membrane Proteins / Memory / Nerve Tissue Proteins Limits: Animals Language: En Journal: J Neurosci Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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