The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.
J Med Chem
; 53(5): 2227-38, 2010 Mar 11.
Article
in En
| MEDLINE
| ID: mdl-20163116
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostaglandin Antagonists
/
Thiophenes
/
Benzoates
/
Receptors, Prostaglandin E
/
Cyclopropanes
/
Analgesics
Limits:
Animals
/
Humans
/
Male
Language:
En
Journal:
J Med Chem
Journal subject:
QUIMICA
Year:
2010
Document type:
Article
Affiliation country:
Canada