Correlation between peripapillary retinal nerve fiber layer thickness and optic nerve head parameters using spectral domain optical coherence tomography.
J Glaucoma
; 19(9): 604-8, 2010 Dec.
Article
in En
| MEDLINE
| ID: mdl-20179617
ABSTRACT
AIM:
To evaluate correlation between peripapillary retinal nerve fiber layer thickness (RNFL) and optic nerve head (ONH) parameters in normal participants using Spectral domain optical coherence tomography (OCT).METHODS:
Sixty-five eyes of 65 healthy participants aged 13-79 years underwent ONH analysis and peripapillary RNFL thickness measurements using spectral domain OCT. The RNFL measurements were correlated with the data obtained with ONH analysis.RESULTS:
The average and quadrant RNFL thickness did not show correlation with optic disc area. A positive correlation was found between average RNFL thickness and rim area (r=0.425, P=0.000) and negative correlation between average RNFL thickness and cup area (r=-0.249, P<0.046).CONCLUSIONS:
In our study, peripapillary RNFL thickness as measured by OCT did not show correlation with optic disc size. Despite a shorter distance between optic disc and circular scan margin, larger discs did not show a thicker RNFL. Interindividual variability of disc area probably minimizes the effect of various ONH size on RNFL thickness measurement.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Optic Disk
/
Retinal Ganglion Cells
/
Tomography, Optical Coherence
/
Nerve Fibers
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Glaucoma
Journal subject:
OFTALMOLOGIA
Year:
2010
Document type:
Article
Affiliation country:
India
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA