Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21.

Cai, Wen-Jie; Wang, Ming-Jie; Ju, Li-Hua; Wang, Cheng; Zhu, Yi-Chun

Cai, Wen-Jie; Wang, Ming-Jie; Ju, Li-Hua; Wang, Cheng; Zhu, Yi-Chun.

Affiliation

Cai WJ; Department of Basic Medicine, University of Shanghai for Science and Technology, Shanghai 200093, People's Republic of China. wjcai@usst.edu.cn

Cell Biol Int ; 34(6): 565-72, 2010 Apr 14.

Article in En | MEDLINE | ID: mdl-20184555

Subject(s)

Colonic Neoplasms/enzymology; Cyclin-Dependent Kinase Inhibitor p21/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Hydrogen Sulfide/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Cell Line, Tumor; Cell Proliferation/drug effects; Colonic Neoplasms/metabolism; Cyclin D1/metabolism; Cyclin-Dependent Kinase Inhibitor p21/physiology; Cystathionine beta-Synthase/genetics; Cystathionine beta-Synthase/metabolism; Cystathionine gamma-Lyase/genetics; Cystathionine gamma-Lyase/metabolism; Extracellular Signal-Regulated MAP Kinases/physiology; HCT116 Cells; Humans; Nitric Oxide/metabolism; Phosphorylation; Proliferating Cell Nuclear Antigen/metabolism; Proto-Oncogene Proteins c-akt/physiology; Resting Phase, Cell Cycle; S Phase; Signal Transduction; Sulfides/chemistry; Sulfides/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colonic Neoplasms / Extracellular Signal-Regulated MAP Kinases / Proto-Oncogene Proteins c-akt / Cyclin-Dependent Kinase Inhibitor p21 / Hydrogen Sulfide Limits: Humans Language: En Journal: Cell Biol Int Year: 2010 Document type: Article Country of publication: United kingdom

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