Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events.

Sacharidou, Anastasia; Koh, Wonshill; Stratman, Amber N; Mayo, Anne M; Fisher, Kevin E; Davis, George E

Sacharidou, Anastasia; Koh, Wonshill; Stratman, Amber N; Mayo, Anne M; Fisher, Kevin E; Davis, George E.

Affiliation

Sacharidou A; Department of Medical Pharmacology and Physiology, University of Missouri School of Medicine, Columbia, MO 85212, USA.

Blood ; 115(25): 5259-69, 2010 Jun 24.

Article in En | MEDLINE | ID: mdl-20215637

Subject(s)

Endothelial Cells/enzymology; Matrix Metalloproteinase 14/metabolism; Neovascularization, Physiologic/physiology; Signal Transduction/physiology; cdc42 GTP-Binding Protein/metabolism; Adaptor Proteins, Signal Transducing/antagonists & inhibitors; Adaptor Proteins, Signal Transducing/metabolism; Antibodies/pharmacology; Cell Adhesion Molecules/metabolism; Cell Cycle Proteins/antagonists & inhibitors; Cell Cycle Proteins/metabolism; Cells, Cultured; Collagen; Humans; Membrane Proteins/antagonists & inhibitors; Membrane Proteins/metabolism; Neovascularization, Physiologic/drug effects; Signal Transduction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Neovascularization, Physiologic / Cdc42 GTP-Binding Protein / Endothelial Cells / Matrix Metalloproteinase 14 Limits: Humans Language: En Journal: Blood Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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