Cardioprotection of exogenous erythropoietin in mice with ligature-induced aortic stenosis: effects on maladaptive cardiac hypertrophy.

Zheng, L; Xu, J; Qiu, W; Liu, X; Zhao, C-M; Chen, D; Chen, Y

Zheng, L; Xu, J; Qiu, W; Liu, X; Zhao, C-M; Chen, D; Chen, Y.

Affiliation

Zheng L; Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

J Physiol Pharmacol ; 61(1): 13-20, 2010 Feb.

Article in En | MEDLINE | ID: mdl-20228410

Subject(s)

Aortic Valve Stenosis/prevention & control; Cardiomegaly/prevention & control; Cardiotonic Agents/therapeutic use; Erythropoietin/therapeutic use; Animals; Aortic Valve Stenosis/metabolism; Aortic Valve Stenosis/pathology; Apoptosis/physiology; Apoptosis Regulatory Proteins/physiology; Cardiomegaly/metabolism; Cardiomegaly/pathology; Disease Models, Animal; Erythropoietin/administration & dosage; Ligation; MAP Kinase Signaling System/physiology; Male; Mice; Mice, Inbred C57BL; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Phosphorylation; Recombinant Proteins/therapeutic use; Tumor Necrosis Factor-alpha/biosynthesis; Tumor Necrosis Factor-alpha/physiology; p38 Mitogen-Activated Protein Kinases/metabolism; p38 Mitogen-Activated Protein Kinases/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Aortic Valve Stenosis / Cardiotonic Agents / Erythropoietin / Cardiomegaly Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Physiol Pharmacol Journal subject: FARMACOLOGIA / FISIOLOGIA Year: 2010 Document type: Article Affiliation country: China Country of publication: Poland

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