A 4-hydroxypyrrolidine-catalyzed mannich reaction of aldehydes: control of anti-selectivity by hydrogen bonding assisted by Brønsted acids.

Gómez-Bengoa, Enrique; Maestro, Miguel; Mielgo, Antonia; Otazo, Itziar; Palomo, Claudio; Velilla, Irene

Gómez-Bengoa, Enrique; Maestro, Miguel; Mielgo, Antonia; Otazo, Itziar; Palomo, Claudio; Velilla, Irene.

Affiliation

Gómez-Bengoa E; Departmento de Química Orgánica I, Universidad del País Vasco, Manuel Lardizabal 3. 20018-San Sebastián, Spain.

Chemistry ; 16(18): 5333-42, 2010 May 10.

Article in En | MEDLINE | ID: mdl-20309975

Subject(s)

Acids/chemistry; Aldehydes/chemistry; Amino Acids/chemistry; Amino Alcohols/chemistry; Imines/chemistry; Pyrrolidines/chemistry; Sulfones/chemistry; Catalysis; Hydrogen Bonding; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Sulfones / Acids / Aldehydes / Amino Acids / Amino Alcohols / Imines Language: En Journal: Chemistry Journal subject: QUIMICA Year: 2010 Document type: Article Affiliation country: Spain Country of publication: Germany

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