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Amide-based inhibitors of p38alpha MAP kinase. Part 2: design, synthesis and SAR of potent N-pyrimidyl amides.
Tester, Richland; Tan, Xuefei; Luedtke, Gregory R; Nashashibi, Imad; Schinzel, Kurt; Liang, Weiling; Jung, Joon; Dugar, Sundeep; Liclican, Albert; Tabora, Jocelyn; Levy, Daniel E; Do, Steven.
Affiliation
  • Tester R; Department of Medicinal Chemistry, Scios Inc. Fremont, CA 94555, USA.
Bioorg Med Chem Lett ; 20(8): 2560-3, 2010 Apr 15.
Article in En | MEDLINE | ID: mdl-20346659
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Protein Kinase Inhibitors / Amides Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2010 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Protein Kinase Inhibitors / Amides Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2010 Document type: Article Affiliation country: United States