Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor.

Kino, Tomoshige; Jaffe, Howard; Amin, Niranjana D; Chakrabarti, Mayukh; Zheng, Ya-Li; Chrousos, George P; Pant, Harish C

Kino, Tomoshige; Jaffe, Howard; Amin, Niranjana D; Chakrabarti, Mayukh; Zheng, Ya-Li; Chrousos, George P; Pant, Harish C.

Affiliation

Kino T; Unit on Molecular Hormone Action, Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1109, USA. kinot@mail.nih.gov

Mol Endocrinol ; 24(5): 941-52, 2010 May.

Article in En | MEDLINE | ID: mdl-20357208

Subject(s)

Brain-Derived Neurotrophic Factor/metabolism; Cyclin-Dependent Kinase 5/metabolism; Receptors, Mineralocorticoid/metabolism; Aldosterone/pharmacology; Animals; Blotting, Western; Brain-Derived Neurotrophic Factor/genetics; Cell Line, Tumor; Cells, Cultured; Corticosterone/metabolism; Cyclin-Dependent Kinase 5/antagonists & inhibitors; Cyclin-Dependent Kinase 5/genetics; Dexamethasone/pharmacology; Humans; Immunoprecipitation; Mass Spectrometry; Phosphorylation/genetics; Phosphorylation/physiology; Polymerase Chain Reaction; Purines/pharmacology; Rats; Receptors, Mineralocorticoid/genetics; Roscovitine; Two-Hybrid System Techniques

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Mineralocorticoid / Brain-Derived Neurotrophic Factor / Cyclin-Dependent Kinase 5 Limits: Animals / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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