Glycal formation in crystals of uridine phosphorylase.

Paul, Debamita; O'Leary, Seán E; Rajashankar, Kanagalaghatta; Bu, Weiming; Toms, Angela; Settembre, Ethan C; Sanders, Jennie M; Begley, Tadhg P; Ealick, Steven E

Paul, Debamita; O'Leary, Seán E; Rajashankar, Kanagalaghatta; Bu, Weiming; Toms, Angela; Settembre, Ethan C; Sanders, Jennie M; Begley, Tadhg P; Ealick, Steven E.

Affiliation

Paul D; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853-1301, USA.

Biochemistry ; 49(16): 3499-509, 2010 Apr 27.

Article in En | MEDLINE | ID: mdl-20364833

Subject(s)

Uridine Phosphorylase/chemistry; Catalytic Domain; Cloning, Molecular; Crystallization; Escherichia coli/enzymology; Floxuridine/pharmacology; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Sulfates/pharmacology; Ultracentrifugation; Uridine/pharmacology; Uridine Phosphorylase/genetics; Uridine Phosphorylase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uridine Phosphorylase Limits: Humans Language: En Journal: Biochemistry Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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