Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase.

Naidu, Pattipati S; Kinsey, Steven G; Guo, Tai L; Cravatt, Benjamin F; Lichtman, Aron H

Naidu, Pattipati S; Kinsey, Steven G; Guo, Tai L; Cravatt, Benjamin F; Lichtman, Aron H.

Affiliation

Naidu PS; Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298, USA.

J Pharmacol Exp Ther ; 334(1): 182-90, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20375198

Subject(s)

Amidohydrolases/antagonists & inhibitors; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Benzoxazines/therapeutic use; Inflammation/drug therapy; Morpholines/therapeutic use; Naphthalenes/therapeutic use; Pain/drug therapy; Amidohydrolases/genetics; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Benzoxazines/pharmacology; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cytokines/immunology; Disease Models, Animal; Edema/drug therapy; Edema/enzymology; Edema/immunology; Edema/metabolism; Female; Hyperalgesia/drug therapy; Hyperalgesia/enzymology; Hyperalgesia/immunology; Hyperalgesia/metabolism; Inflammation/enzymology; Inflammation/immunology; Inflammation/metabolism; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines/pharmacology; Naphthalenes/pharmacology; Pain/enzymology; Pain/immunology; Pain/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Anti-Inflammatory Agents, Non-Steroidal / Morpholines / Benzoxazines / Amidohydrolases / Inflammation / Naphthalenes Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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