VEGF-induced angiogenesis following localized delivery via injectable, low viscosity poly(trimethylene carbonate).

Amsden, Brian G; Timbart, Laurianne; Marecak, Dale; Chapanian, Rafi; Tse, M Yat; Pang, Stephen C

Amsden, Brian G; Timbart, Laurianne; Marecak, Dale; Chapanian, Rafi; Tse, M Yat; Pang, Stephen C.

Affiliation

Amsden BG; Department of Chemical Engineering, Queen's University, Kingston, Ontario, Canada K7L 3N6. brian.amsden@chee.queensu.ca

J Control Release ; 145(2): 109-15, 2010 Jul 14.

Article in En | MEDLINE | ID: mdl-20381557

Subject(s)

Dioxanes/chemistry; Neovascularization, Physiologic; Polymers/chemistry; Vascular Endothelial Growth Factor A/administration & dosage; Vascular Endothelial Growth Factor A/pharmacology; 1-Octanol; Animals; Aorta/cytology; Cattle; Cell Proliferation/drug effects; Chemistry, Pharmaceutical; Dioxanes/chemical synthesis; Endothelial Cells/cytology; Endothelial Cells/metabolism; Freeze Drying; Humans; Injections; Male; Molecular Weight; Neovascularization, Physiologic/physiology; Polymerization; Rats; Rats, Wistar; Recombinant Proteins/chemistry; Recombinant Proteins/pharmacology; Serum Albumin/chemistry; Serum Albumin/genetics; Solubility; Trehalose; Vascular Endothelial Growth Factor A/chemistry; Vascular Endothelial Growth Factors/administration & dosage; Vascular Endothelial Growth Factors/chemistry; Viscosity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / Neovascularization, Physiologic / Vascular Endothelial Growth Factor A / Dioxanes Limits: Animals / Humans / Male Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2010 Document type: Article Country of publication: Netherlands

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