A molecular pharmacology study into the anti-inflammatory actions of Euphorbia hirta L. on the LPS-induced RAW 264.7 cells through selective iNOS protein inhibition.

Shih, Mei-Fen; Cheng, Yih-Dih; Shen, Chia-Rui; Cherng, Jong-Yuh

Shih, Mei-Fen; Cheng, Yih-Dih; Shen, Chia-Rui; Cherng, Jong-Yuh.

Affiliation

Shih MF; Department of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan, ROC.

J Nat Med ; 64(3): 330-5, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20390370

Subject(s)

Anti-Inflammatory Agents/pharmacology; Euphorbia/chemistry; Lipopolysaccharides/toxicity; Macrophages/drug effects; Macrophages/metabolism; Nitric Oxide Synthase Type II/metabolism; Plant Extracts/pharmacology; Animals; Anti-Inflammatory Agents/chemistry; Blotting, Western; Cell Line; Dinoprostone/metabolism; Enzyme-Linked Immunosorbent Assay; Interleukin-6/metabolism; Mice; Molecular Structure; Nitric Oxide/metabolism; Nitric Oxide Synthase Type II/genetics; Plant Extracts/chemistry; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Lipopolysaccharides / Euphorbia / Nitric Oxide Synthase Type II / Macrophages / Anti-Inflammatory Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Nat Med Journal subject: TERAPIAS COMPLEMENTARES Year: 2010 Document type: Article

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