Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice.

Jackson, K J; Marks, M J; Vann, R E; Chen, X; Gamage, T F; Warner, J A; Damaj, M I

Jackson, K J; Marks, M J; Vann, R E; Chen, X; Gamage, T F; Warner, J A; Damaj, M I.

Affiliation

Jackson KJ; Department of Psychiatry, Pharmacology/Toxicology, Virginia Commonwealth University, Richmond, VA 23298-0613, USA. jacksonkj@vcu.edu

J Pharmacol Exp Ther ; 334(1): 137-46, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20400469

Subject(s)

Behavior, Animal/drug effects; Nicotine/pharmacology; Receptors, Nicotinic/physiology; Analgesics, Opioid/pharmacology; Animals; Body Temperature; Brain/drug effects; Brain/metabolism; Dose-Response Relationship, Drug; Hypothermia/chemically induced; Hypothermia/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine/pharmacology; Motor Activity/drug effects; Nicotinic Agonists/pharmacology; Pain/metabolism; Pain Threshold/drug effects; Protein Binding; Receptors, Nicotinic/genetics; Spinal Cord/drug effects; Spinal Cord/metabolism; Synaptosomes/drug effects; Synaptosomes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Animal / Receptors, Nicotinic / Nicotine Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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