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Preclinical PK and PD studies on 2'-O-methyl-phosphorothioate RNA antisense oligonucleotides in the mdx mouse model.
Heemskerk, Hans; de Winter, Christa; van Kuik, Petra; Heuvelmans, Niki; Sabatelli, Patrizia; Rimessi, Paola; Braghetta, Paola; van Ommen, Gert-Jan B; de Kimpe, Sjef; Ferlini, Alessandra; Aartsma-Rus, Annemieke; van Deutekom, Judith C T.
Affiliation
  • Heemskerk H; Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Mol Ther ; 18(6): 1210-7, 2010 Jun.
Article in En | MEDLINE | ID: mdl-20407428
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Antisense / Phosphorothioate Oligonucleotides Type of study: Guideline Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2010 Document type: Article Affiliation country: Netherlands Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Antisense / Phosphorothioate Oligonucleotides Type of study: Guideline Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2010 Document type: Article Affiliation country: Netherlands Country of publication: United States