Efavirenz directly modulates the oestrogen receptor and induces breast cancer cell growth.

Sikora, M J; Rae, J M; Johnson, M D; Desta, Z

Sikora, M J; Rae, J M; Johnson, M D; Desta, Z.

Affiliation

Sikora MJ; Department of Pharmacology, University of Michigan Medical Center, Ann Arbor, MI, USA.

HIV Med ; 11(9): 603-7, 2010 Oct 01.

Article in En | MEDLINE | ID: mdl-20408889

Subject(s)

Benzoxazines/pharmacology; Breast Neoplasms/metabolism; Estradiol/analogs & derivatives; Estrogen Antagonists/pharmacology; Estrogen Receptor alpha/agonists; Reverse Transcriptase Inhibitors/pharmacology; Alkynes; Benzoxazines/adverse effects; Breast Neoplasms/chemically induced; Cell Proliferation/drug effects; Cells, Cultured; Cyclopropanes; Dose-Response Relationship, Drug; Estradiol/pharmacology; Estrogen Receptor alpha/antagonists & inhibitors; Female; Fulvestrant; Gynecomastia/chemically induced; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Reverse Transcriptase Inhibitors/adverse effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Reverse Transcriptase Inhibitors / Benzoxazines / Estrogen Receptor alpha / Estradiol / Estrogen Antagonists Limits: Female / Humans / Male Language: En Journal: HIV Med Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2010 Document type: Article Affiliation country: United States Country of publication: United kingdom

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