Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus.
B-ENT
; 6(1): 67-72, 2010.
Article
in En
| MEDLINE
| ID: mdl-20420085
ABSTRACT
OBJECTIVE:
To present a clinical case of an adult affected by Langerhans cell histiocytosis with bilateral, non-simultaneous, involvement of the temporal bone, associated with diabetes insipidus and to review the literature.METHODOLOGY:
A rare case of bilateral temporal bone involvement of Langerhans cell histiocytosis in a 42-year-old woman affected by diabetes insipidus is reported. We present patient's clinical history supported by radiologic, histopathologic and audiologic findings.RESULTS:
The patient was submitted to a series of otologic surgical procedures due to the progression of the disease. Ossicular chain was always preserved, so that conservative surgery (canal wall-up technique) was performed, permitting the achievement of good hearing results, bilaterally.CONCLUSIONS:
Temporal bone involvement of Langerhans cell histiocytosis may lead to a progressive chronic disease. However, the ossicular chain can remain uninvolved, making a conservative surgical treatment possible. Careful follow-up is essential for detecting new lesions and serial CT scans are mandatory.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Histiocytosis, Langerhans-Cell
/
Diabetes Insipidus
Type of study:
Etiology_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
B-ENT
Journal subject:
OTORRINOLARINGOLOGIA
Year:
2010
Document type:
Article
Affiliation country:
Italy