Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis.

Lin, Chang-Jun; Ho, Hung-Yao; Cheng, Mei-Ling; You, Tsai-Hong; Cheng, Tsai-Hong; Yu, Jau-Song; Chiu, Daniel Tsun-Yee

Lin, Chang-Jun; Ho, Hung-Yao; Cheng, Mei-Ling; You, Tsai-Hong; Cheng, Tsai-Hong; Yu, Jau-Song; Chiu, Daniel Tsun-Yee.

Affiliation

Lin CJ; Graduate Institute of Medical Biotechnology, Chang Gung University, Tao-Yuan, Taiwan.

Free Radic Biol Med ; 49(3): 361-73, 2010 Aug 01.

Article in En | MEDLINE | ID: mdl-20420899

Subject(s)

Apoptosis/drug effects; Glucosephosphate Dehydrogenase/genetics; Hydrogen Peroxide/pharmacology; Acetylcysteine/pharmacology; Anthracenes/pharmacology; Dual Specificity Phosphatase 1/antagonists & inhibitors; Dual Specificity Phosphatase 1/metabolism; Flavonoids/pharmacology; Gene Knockdown Techniques; Hep G2 Cells; Humans; Imidazoles/pharmacology; Mitogen-Activated Protein Kinases/metabolism; Protein Tyrosine Phosphatases/antagonists & inhibitors; Pyridines/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Glucosephosphate Dehydrogenase / Hydrogen Peroxide Limits: Humans Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2010 Document type: Article Affiliation country: Taiwan Country of publication: United States

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