Aciclovir-resistant herpes keratitis.

Choong, Keat; Walker, Nathan J; Apel, Andrew Jg; Whitby, Michael

Choong, Keat; Walker, Nathan J; Apel, Andrew Jg; Whitby, Michael.

Affiliation

Choong K; Infection Management Services, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Qld 4102, Australia. keatchoong@optusnet.com.au

Clin Exp Ophthalmol ; 38(3): 309-13, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20447128

ABSTRACT

Herpes simplex virus (HSV) keratitis is a common cause of ocular morbidity. Resistance to aciclovir is probably under recognized. We describe three cases of aciclovir-resistant herpes simplex virus keratitis treated with systemic foscarnet and present a review of the pharmacological options available to manage this condition.

Subject(s)

Acyclovir/therapeutic use; Antiviral Agents/therapeutic use; Drug Resistance, Viral; Keratitis, Herpetic/drug therapy; Acyclovir/administration & dosage; Administration, Oral; Administration, Topical; Aged, 80 and over; Antiviral Agents/administration & dosage; Blindness/virology; Humans; Keratitis, Herpetic/complications; Male; Middle Aged; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Acyclovir / Keratitis, Herpetic / Drug Resistance, Viral Limits: Aged80 / Humans / Male / Middle aged Language: En Journal: Clin Exp Ophthalmol Journal subject: OFTALMOLOGIA Year: 2010 Document type: Article Affiliation country: Australia Country of publication: Australia

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