Anticancer potential of animal venoms and toxins.
Indian J Exp Biol
; 48(2): 93-103, 2010 Feb.
Article
in En
| MEDLINE
| ID: mdl-20455317
Anticancer drug development from natural resources are ventured throughout the world. Animal venoms and toxins a potential bio resource and a therapeutic tool were known to man for centuries through folk and traditional knowledge. The biodiversity of venoms and toxins made it a unique source of leads and structural templates from which new therapeutic agents may be developed. Venoms of several animal species (snake, scorpion, toad, frog etc) and their active components (protein and non protein toxins, peptides, enzymes, etc) have shown therapeutic potential against cancer. In the present review, the anticancer potential of venoms and toxins from snakes, scorpions, toads and frogs has been discussed. Some of these molecules are in the clinical trials and may find their way towards anticancer drug development in the near future. The implications of combination therapy of natural products in cancer have been discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Venoms
/
Neoplasms
/
Antineoplastic Agents
Type of study:
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Indian J Exp Biol
Year:
2010
Document type:
Article
Affiliation country:
India
Country of publication:
India