OrfA downregulates feline immunodeficiency virus primary receptor CD134 on the host cell surface and is important in viral infection.

Hong, Yang; Fink, Elizabeth; Hu, Qiong-Ying; Kiosses, William B; Elder, John H

Hong, Yang; Fink, Elizabeth; Hu, Qiong-Ying; Kiosses, William B; Elder, John H.

Affiliation

Hong Y; Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, USA.

J Virol ; 84(14): 7225-32, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20463078

Subject(s)

Immunodeficiency Virus, Feline/physiology; Receptors, OX40/metabolism; T-Lymphocytes/virology; Viral Proteins/metabolism; Animals; Cats; Cell Line; Cell Membrane/metabolism; Cell Separation; Down-Regulation; Humans; Immunodeficiency Virus, Feline/genetics; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Small Interfering/genetics; Receptors, OX40/genetics; Viral Proteins/genetics; Virus Internalization; Virus Release

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / T-Lymphocytes / Immunodeficiency Virus, Feline / Receptors, OX40 Limits: Animals / Humans Language: En Journal: J Virol Year: 2010 Document type: Article Affiliation country: United States

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