Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair.

Hirsch, M L; Green, L; Porteus, M H; Samulski, R J

Hirsch, M L; Green, L; Porteus, M H; Samulski, R J.

Affiliation

Hirsch ML; UNC Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7352, USA.

Gene Ther ; 17(9): 1175-80, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20463753

Subject(s)

Dependovirus/genetics; Endodeoxyribonucleases/genetics; Gene Targeting; Genetic Vectors/genetics; Cells, Cultured; DNA/metabolism; DNA Breaks, Double-Stranded; DNA Repair; DNA, Single-Stranded/metabolism; Endodeoxyribonucleases/metabolism; Humans; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dependovirus / Gene Targeting / Endodeoxyribonucleases / Genetic Vectors Limits: Humans Language: En Journal: Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2010 Document type: Article Affiliation country: United States

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