MT1-MMP association with membrane lipid rafts facilitates G-CSF--induced hematopoietic stem/progenitor cell mobilization.

Shirvaikar, Neeta; Marquez-Curtis, Leah A; Shaw, Andrew R; Turner, A Robert; Janowska-Wieczorek, Anna

Shirvaikar, Neeta; Marquez-Curtis, Leah A; Shaw, Andrew R; Turner, A Robert; Janowska-Wieczorek, Anna.

Affiliation

Shirvaikar N; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

Exp Hematol ; 38(9): 823-35, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20471446

Subject(s)

Gene Expression Regulation, Enzymologic/drug effects; Granulocyte Colony-Stimulating Factor/pharmacology; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells/enzymology; Matrix Metalloproteinase 14/biosynthesis; Membrane Microdomains/enzymology; Up-Regulation/drug effects; Cell Movement; Cells, Cultured; Coculture Techniques; Enzyme Activation/drug effects; Enzyme Precursors/metabolism; Fibroblasts/cytology; Fibroblasts/metabolism; Gelatinases/metabolism; Hematopoietic Stem Cells/cytology; Humans; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation/drug effects; Signal Transduction/drug effects; Stromal Cells/cytology; Stromal Cells/metabolism; beta-Cyclodextrins/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Gene Expression Regulation, Enzymologic / Up-Regulation / Granulocyte Colony-Stimulating Factor / Hematopoietic Stem Cell Mobilization / Membrane Microdomains / Matrix Metalloproteinase 14 Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Exp Hematol Year: 2010 Document type: Article Affiliation country: Canada Country of publication: Netherlands

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