Two-stage phase I dose-escalation study of intratumoral reovirus type 3 dearing and palliative radiotherapy in patients with advanced cancers.

Harrington, Kevin J; Karapanagiotou, Eleni M; Roulstone, Victoria; Twigger, Katie R; White, Christine L; Vidal, Laura; Beirne, Debbie; Prestwich, Robin; Newbold, Kate; Ahmed, Merina; Thway, Khin; Nutting, Christopher M; Coffey, Matt; Harris, Dean; Vile, Richard G; Pandha, Hardev S; Debono, Johann S; Melcher, Alan A

Harrington, Kevin J; Karapanagiotou, Eleni M; Roulstone, Victoria; Twigger, Katie R; White, Christine L; Vidal, Laura; Beirne, Debbie; Prestwich, Robin; Newbold, Kate; Ahmed, Merina; Thway, Khin; Nutting, Christopher M; Coffey, Matt; Harris, Dean; Vile, Richard G; Pandha, Hardev S; Debono, Johann S; Melcher, Alan A.

Affiliation

Harrington KJ; The Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom. kevin.harrington@icr.ac.uk

Clin Cancer Res ; 16(11): 3067-77, 2010 Jun 01.

Article in En | MEDLINE | ID: mdl-20484020

Subject(s)

Mammalian orthoreovirus 3; Neoplasms/therapy; Oncolytic Virotherapy; Adult; Aged; Antibodies, Viral/analysis; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Neoplasms/radiotherapy; Oncolytic Virotherapy/adverse effects; Oncolytic Virotherapy/methods; Radiotherapy Dosage; Tissue Distribution; Virus Replication; Virus Shedding

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mammalian orthoreovirus 3 / Oncolytic Virotherapy / Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2010 Document type: Article Affiliation country: United kingdom

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