Aberrant methylation of breast and ovarian cancer susceptibility gene 1 in chemosensitive human ovarian cancer cells does not involve the phosphatidylinositol 3'-kinase-Akt pathway.

Wang, Yan-Qiu; Zhang, Jia-Rong; Li, Shuang-Di; He, Yin-Yan; Yang, Yi-Xia; Liu, Xue-Lian; Wan, Xiao-Ping

Wang, Yan-Qiu; Zhang, Jia-Rong; Li, Shuang-Di; He, Yin-Yan; Yang, Yi-Xia; Liu, Xue-Lian; Wan, Xiao-Ping.

Affiliation

Wang YQ; Department of Obstetrics and Gynecology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China.

Cancer Sci ; 101(7): 1618-23, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20487263

Subject(s)

Breast Neoplasms/genetics; DNA Methylation; Genes, BRCA1; Genetic Predisposition to Disease; Ovarian Neoplasms/genetics; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Cell Line, Tumor; DNA, Neoplasm/metabolism; Female; Gene Expression Regulation, Neoplastic; Humans; Tumor Suppressor Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Breast Neoplasms / Genes, BRCA1 / DNA Methylation / Phosphatidylinositol 3-Kinases / Genetic Predisposition to Disease / Proto-Oncogene Proteins c-akt Limits: Female / Humans Language: En Journal: Cancer Sci Year: 2010 Document type: Article Affiliation country: China Country of publication: United kingdom

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