Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1.

Keck, Gary E; Poudel, Yam B; Rudra, Arnab; Stephens, Jeffrey C; Kedei, Noemi; Lewin, Nancy E; Peach, Megan L; Blumberg, Peter M

Keck, Gary E; Poudel, Yam B; Rudra, Arnab; Stephens, Jeffrey C; Kedei, Noemi; Lewin, Nancy E; Peach, Megan L; Blumberg, Peter M.

Affiliation

Keck GE; Department of Chemistry, University of Utah, 315 South 1400 East, Rm 2020, Salt Lake City, UT 84112, USA. keck@chem.utah.edu

Angew Chem Int Ed Engl ; 49(27): 4580-4, 2010 Jun 21.

Article in En | MEDLINE | ID: mdl-20491108

Subject(s)

Bryostatins/chemical synthesis; Oxygen/chemistry; Bryostatins/pharmacology; Cell Adhesion/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Humans; Models, Molecular; Molecular Structure; Protein Kinase C-delta/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Bryostatins Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2010 Document type: Article Affiliation country: United States Country of publication: Germany

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