?-Galactoside soluble lectin from human brain: complete amino acid sequence.

ABSTRACT

A soluble lectin from human brain, specific for ?-galactoside-containing glycoconjugates, has been sequenced and compared with a similar protein purified from human placenta. The sequence was established from the analysis of the peptides obtained by chemical and proteolytic cleavage. The brain lectin has a complete homology with that of placenta. This and similar results observed in other mammals strongly suggest that there is only one gene, per species, encoding for this protein.