No effect of dopamine depletion on the binding of the high-affinity D 2/3 radiotracer [11C]FLB 457 in the human cortex.

Frankle, W Gordon; Mason, N Scott; Rabiner, Eugenii A; Ridler, Khanum; May, Maureen A; Asmonga, Deanna; Chen, Chi-Min; Kendro, Steve; Cooper, Thomas B; Mathis, Chester A; Narendran, Rajesh

Frankle, W Gordon; Mason, N Scott; Rabiner, Eugenii A; Ridler, Khanum; May, Maureen A; Asmonga, Deanna; Chen, Chi-Min; Kendro, Steve; Cooper, Thomas B; Mathis, Chester A; Narendran, Rajesh.

Affiliation

Frankle WG; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA. franklewg@upmc.edu

Synapse ; 64(12): 879-85, 2010 Dec.

Article in En | MEDLINE | ID: mdl-20506387

Subject(s)

Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; Dopamine/deficiency; Pyrrolidines/metabolism; Receptors, Dopamine D2/metabolism; Receptors, Dopamine D3/metabolism; Salicylamides/metabolism; Adult; Binding, Competitive/drug effects; Binding, Competitive/physiology; Carbon Radioisotopes/metabolism; Cerebral Cortex/diagnostic imaging; Dopamine/physiology; Dopamine Antagonists/metabolism; Female; Humans; Male; Radionuclide Imaging; Synaptic Transmission/drug effects; Synaptic Transmission/physiology; Young Adult; alpha-Methyltyrosine/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Dopamine / Cerebral Cortex / Salicylamides / Receptors, Dopamine D2 / Receptors, Dopamine D3 Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male Language: En Journal: Synapse Journal subject: NEUROLOGIA Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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