Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose.

Crespo, Francisco Luna; Sobrado, Veronica R; Gomez, Laura; Cervera, Ana M; McCreath, Kenneth J

Crespo, Francisco Luna; Sobrado, Veronica R; Gomez, Laura; Cervera, Ana M; McCreath, Kenneth J.

Affiliation

Crespo FL; Laboratory of Cellular Signaling, Department of Regenerative Cardiology, Centro Nacional de Investigaciones Cardiovasculares, (CNIC) Carlos III, Madrid, Spain.

Stem Cells ; 28(7): 1132-42, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20506541

Subject(s)

Cell Differentiation/drug effects; Embryonic Stem Cells/metabolism; Glucose/pharmacology; Mitochondria/metabolism; Myocytes, Cardiac/cytology; Myocytes, Cardiac/metabolism; Reactive Oxygen Species/metabolism; Animals; Cell Culture Techniques; Embryonic Stem Cells/cytology; Embryonic Stem Cells/drug effects; Gene Expression Regulation; Mice; Myocytes, Cardiac/drug effects; NADPH Oxidase 4; NADPH Oxidases/genetics; NADPH Oxidases/metabolism; Phosphorylation; p38 Mitogen-Activated Protein Kinases/genetics; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Reactive Oxygen Species / Myocytes, Cardiac / Embryonic Stem Cells / Glucose / Mitochondria Limits: Animals Language: En Journal: Stem Cells Year: 2010 Document type: Article Affiliation country: Spain Country of publication: United kingdom

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