Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics.

Lu, Pinyi; Bevan, David R; Lewis, Stephanie N; Hontecillas, Raquel; Bassaganya-Riera, Josep

Lu, Pinyi; Bevan, David R; Lewis, Stephanie N; Hontecillas, Raquel; Bassaganya-Riera, Josep.

Affiliation

Lu P; Genetics, Bioinformatics, and Computational Biology Program, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

J Mol Model ; 17(3): 543-53, 2011 Mar.

Article in En | MEDLINE | ID: mdl-20512604

Subject(s)

Diabetes Mellitus, Type 2/drug therapy; Hypoglycemic Agents/chemistry; Membrane Proteins/chemistry; Models, Molecular; Nuclear Proteins/chemistry; Abscisic Acid/chemistry; Abscisic Acid/metabolism; Amino Acid Sequence; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Diabetes Mellitus, Type 2/prevention & control; Humans; Ligands; Molecular Sequence Data; PPAR gamma/agonists; PPAR gamma/chemistry; PPAR gamma/metabolism; Phosphate-Binding Proteins; Protein Structure, Tertiary; Receptors, G-Protein-Coupled/chemistry; Sequence Alignment; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Models, Molecular / Diabetes Mellitus, Type 2 / Hypoglycemic Agents / Membrane Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Mol Model Journal subject: BIOLOGIA MOLECULAR Year: 2011 Document type: Article Affiliation country: United States Country of publication: Germany

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