Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation.

Puttur, Franz K; Fernandez, Marian A; White, Rose; Roediger, Ben; Cunningham, Anthony L; Weninger, Wolfgang; Jones, Cheryl A

Puttur, Franz K; Fernandez, Marian A; White, Rose; Roediger, Ben; Cunningham, Anthony L; Weninger, Wolfgang; Jones, Cheryl A.

Affiliation

Puttur FK; Sydney Medical School, University of Sydney, Sydney, Australia.

J Immunol ; 185(1): 477-87, 2010 Jul 01.

Article in En | MEDLINE | ID: mdl-20519652

Subject(s)

Apoptosis/immunology; Cadherins/antagonists & inhibitors; Cell Migration Inhibition/immunology; Down-Regulation/immunology; Herpesvirus 2, Human/immunology; Langerhans Cells/immunology; Receptors, Antigen, T-Cell, gamma-delta/biosynthesis; Receptors, Antigen, T-Cell, gamma-delta/physiology; Animals; Cadherins/physiology; Ear, External; Epidermis/immunology; Epidermis/metabolism; Epidermis/virology; Female; Herpesvirus 1, Human/immunology; Langerhans Cells/pathology; Langerhans Cells/virology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organ Culture Techniques; Receptors, Antigen, T-Cell, gamma-delta/antagonists & inhibitors; T-Lymphocyte Subsets/immunology; T-Lymphocyte Subsets/pathology; T-Lymphocyte Subsets/virology; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Migration Inhibition / Cadherins / Down-Regulation / Langerhans Cells / Receptors, Antigen, T-Cell, gamma-delta / Apoptosis / Herpesvirus 2, Human Limits: Animals Language: En Journal: J Immunol Year: 2010 Document type: Article Affiliation country: Australia Country of publication: United States

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