Bortezomib affects the function of human B cells: possible implications for desensitization protocols.

Heidt, S; Roelen, D L; Vergunst, M; Doxiadis, I I N; Claas, F H J; Mulder, A

Heidt, S; Roelen, D L; Vergunst, M; Doxiadis, I I N; Claas, F H J; Mulder, A.

Affiliation

Heidt S; Dept. of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

Clin Transpl ; : 387-92, 2009.

Article in En | MEDLINE | ID: mdl-20524303

Subject(s)

B-Lymphocytes/immunology; Boronic Acids/pharmacology; Desensitization, Immunologic/methods; HLA Antigens/immunology; Protease Inhibitors/pharmacology; Pyrazines/pharmacology; Antigens, CD19/analysis; Apoptosis/drug effects; Autoantibodies/drug effects; Autoantibodies/immunology; B-Lymphocytes/drug effects; B-Lymphocytes/physiology; Blood Banks; Bortezomib; Humans; Immunoglobulin G/blood; Immunoglobulin G/drug effects; Immunoglobulin M/blood; Immunoglobulin M/drug effects; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/immunology; Leukocytes, Mononuclear/physiology; Lymphocyte Activation/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Pyrazines / Boronic Acids / B-Lymphocytes / Desensitization, Immunologic / HLA Antigens Limits: Humans Language: En Journal: Clin Transpl Journal subject: TRANSPLANTE Year: 2009 Document type: Article Affiliation country: Netherlands Country of publication: United States

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