Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats.

Kuwabara, A; Satoh, M; Tomita, N; Sasaki, T; Kashihara, N

Kuwabara, A; Satoh, M; Tomita, N; Sasaki, T; Kashihara, N.

Affiliation

Kuwabara A; Division of Nephrology and Hypertension, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan.

Diabetologia ; 53(9): 2056-65, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20526760

Subject(s)

Endothelial Cells/pathology; Kidney Glomerulus/pathology; Oxidative Stress/physiology; Albuminuria/drug therapy; Albuminuria/metabolism; Albuminuria/pathology; Angiotensin II Type 1 Receptor Blockers/therapeutic use; Animals; Biphenyl Compounds/therapeutic use; Blotting, Western; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Hemodynamics/drug effects; Irbesartan; Kidney Glomerulus/drug effects; Kidney Glomerulus/metabolism; Male; Oxidative Stress/drug effects; Rats; Rats, Zucker; Reactive Oxygen Species/metabolism; Tetrazoles/therapeutic use

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Endothelial Cells / Kidney Glomerulus Limits: Animals Language: En Journal: Diabetologia Year: 2010 Document type: Article Affiliation country: Japan Country of publication: Germany

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google