A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer.

Pang, Roberta; Law, Wai Lun; Chu, Andrew C Y; Poon, Jensen T; Lam, Colin S C; Chow, Ariel K M; Ng, Lui; Cheung, Leonard W H; Lan, Xiao R; Lan, Hui Y; Tan, Victoria P Y; Yau, Thomas C; Poon, Ronnie T; Wong, Benjamin C Y

Pang, Roberta; Law, Wai Lun; Chu, Andrew C Y; Poon, Jensen T; Lam, Colin S C; Chow, Ariel K M; Ng, Lui; Cheung, Leonard W H; Lan, Xiao R; Lan, Hui Y; Tan, Victoria P Y; Yau, Thomas C; Poon, Ronnie T; Wong, Benjamin C Y.

Affiliation

Pang R; Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR.

Cell Stem Cell ; 6(6): 603-15, 2010 Jun 04.

Article in En | MEDLINE | ID: mdl-20569697

Subject(s)

Biomarkers, Tumor/biosynthesis; Carcinoma/diagnosis; Colorectal Neoplasms/diagnosis; Dipeptidyl Peptidase 4/biosynthesis; Liver Neoplasms/diagnosis; Neoplastic Stem Cells/metabolism; Animals; Apoptosis/drug effects; Apoptosis/genetics; Biomarkers, Tumor/genetics; Carcinoma/drug therapy; Carcinoma/genetics; Carcinoma/metabolism; Carcinoma/physiopathology; Carcinoma/secondary; Cell Migration Assays; Cell Transformation, Neoplastic/genetics; Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/genetics; Colorectal Neoplasms/metabolism; Colorectal Neoplasms/pathology; Colorectal Neoplasms/physiopathology; Dipeptidyl Peptidase 4/genetics; Disease Progression; Drug Resistance, Neoplasm/genetics; Fluorouracil/pharmacology; Follow-Up Studies; Gene Expression Profiling; Humans; Liver Neoplasms/drug therapy; Liver Neoplasms/genetics; Liver Neoplasms/metabolism; Liver Neoplasms/physiopathology; Liver Neoplasms/secondary; Mice; Mice, SCID; Neoplasm Invasiveness/genetics; Neoplasm Transplantation; Neoplastic Stem Cells/drug effects; Neoplastic Stem Cells/pathology; Organoplatinum Compounds/pharmacology; Oxaliplatin; Prognosis; RNA, Small Interfering/genetics; Tumor Burden/drug effects; Tumor Burden/genetics; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Carcinoma / Colorectal Neoplasms / Biomarkers, Tumor / Dipeptidyl Peptidase 4 / Liver Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Cell Stem Cell Year: 2010 Document type: Article Country of publication: United States

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