Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin.

Wähe, Anna; Kasmapour, Bahram; Schmaderer, Christoph; Liebl, David; Sandhoff, Konrad; Nykjaer, Anders; Griffiths, Gareth; Gutierrez, Maximiliano G

Wähe, Anna; Kasmapour, Bahram; Schmaderer, Christoph; Liebl, David; Sandhoff, Konrad; Nykjaer, Anders; Griffiths, Gareth; Gutierrez, Maximiliano G.

Affiliation

Wähe A; European Molecular Biology Laboratory, Postfach 102209, 69117 Heidelberg, Germany.

J Cell Sci ; 123(Pt 14): 2502-11, 2010 Jul 15.

Article in En | MEDLINE | ID: mdl-20571055

Subject(s)

Adaptor Proteins, Vesicular Transport/metabolism; Golgi Apparatus/metabolism; Macrophages/metabolism; Saposins/metabolism; Sphingomyelin Phosphodiesterase/metabolism; Adaptor Proteins, Vesicular Transport/genetics; Animals; Brefeldin A/pharmacology; Cell Line, Tumor; Female; Golgi Apparatus/drug effects; Macrophages/drug effects; Macrophages/pathology; Mice; Mice, Inbred BALB C; Mice, Knockout; Phagocytosis; Phagosomes/metabolism; Protein Transport/drug effects; Protein Transport/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sphingomyelin Phosphodiesterase / Adaptor Proteins, Vesicular Transport / Saposins / Golgi Apparatus / Macrophages Limits: Animals Language: En Journal: J Cell Sci Year: 2010 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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