Thrombogenesis with continuous blood flow in the inferior vena cava. A novel mouse model.

Diaz, José A; Hawley, Angela E; Alvarado, Christine M; Berguer, Alexandra M; Baker, Nichole K; Wrobleski, Shirley K; Wakefield, Thomas W; Lucchesi, Benedict R; Myers, Daniel D

Diaz, José A; Hawley, Angela E; Alvarado, Christine M; Berguer, Alexandra M; Baker, Nichole K; Wrobleski, Shirley K; Wakefield, Thomas W; Lucchesi, Benedict R; Myers, Daniel D.

Affiliation

Diaz JA; Department of Surgery, Section of Vascular Surgery, University of Michigan, Ann Arbor, Michigan 48109-0654, USA. josediaz@med.umich.edu

Thromb Haemost ; 104(2): 366-75, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20589322

Subject(s)

Blood Coagulation; Disease Models, Animal; Vena Cava, Inferior/physiopathology; Venous Thrombosis/physiopathology; Animals; Blood Coagulation/genetics; Electrolysis; Endothelial Cells/metabolism; Enoxaparin/pharmacology; Fibrinolytic Agents/pharmacology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Neutrophil Infiltration; P-Selectin/blood; P-Selectin/genetics; Plasminogen Activator Inhibitor 1/deficiency; Plasminogen Activator Inhibitor 1/genetics; Regional Blood Flow; Thrombophilia/blood; Thrombophilia/genetics; Thrombophilia/physiopathology; Time Factors; Ultrasonography, Doppler, Color; Vena Cava, Inferior/diagnostic imaging; Vena Cava, Inferior/injuries; Vena Cava, Inferior/metabolism; Vena Cava, Inferior/ultrastructure; Venous Thrombosis/blood; Venous Thrombosis/diagnosis; Venous Thrombosis/genetics; Venous Thrombosis/prevention & control; von Willebrand Factor/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vena Cava, Inferior / Blood Coagulation / Venous Thrombosis / Disease Models, Animal Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Thromb Haemost Year: 2010 Document type: Article Affiliation country: United States

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