Prophylactic treatment with a G glycoprotein monoclonal antibody reduces pulmonary inflammation in respiratory syncytial virus (RSV)-challenged naive and formalin-inactivated RSV-immunized BALB/c mice.

Radu, Gertrud U; Caidi, Hayat; Miao, Congrong; Tripp, Ralph A; Anderson, Larry J; Haynes, Lia M

Radu, Gertrud U; Caidi, Hayat; Miao, Congrong; Tripp, Ralph A; Anderson, Larry J; Haynes, Lia M.

Affiliation

Radu GU; Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Mailstop G-18, Atlanta, GA 30333, USA.

J Virol ; 84(18): 9632-6, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20592094

Subject(s)

Antibodies, Monoclonal/therapeutic use; Antibodies, Viral/therapeutic use; Chemoprevention/methods; Pneumonia/prevention & control; Respiratory Syncytial Virus Infections/prevention & control; Respiratory Syncytial Virus Vaccines/immunology; Viral Fusion Proteins/immunology; Animals; Antibodies, Monoclonal/immunology; Antibodies, Viral/immunology; Body Weight; Bronchoalveolar Lavage Fluid/chemistry; Bronchoalveolar Lavage Fluid/cytology; Mice; Mice, Inbred BALB C; Pneumonia/immunology; Pneumonia/pathology; Respiratory Syncytial Virus Infections/immunology; Respiratory Syncytial Virus Infections/pathology; Respiratory Syncytial Viruses/immunology; Respiratory Syncytial Viruses/pathogenicity; Vaccines, Inactivated/immunology; Viral Load

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia / Viral Fusion Proteins / Respiratory Syncytial Virus Infections / Chemoprevention / Respiratory Syncytial Virus Vaccines / Antibodies, Monoclonal / Antibodies, Viral Limits: Animals Language: En Journal: J Virol Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google